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Pryor Creek or Pryor is a city in and county seat of Mayes County, Oklahoma, United States. The population was 8,659 at the 2000 census, compared to 9,539 in the 2010 census.
Originally named Coo-Y-Yah, Cherokee for "place of the huckleberries", it was renamed Pryor Creek in 1887 which was the name of the local railroad station, which is turn was named for the nearby creek. Due to confusion in distinguishing handwritten mailing addresses to Pryor Creek and Pond Creek, the U.S. Postal Service name for the city was shortened to Pryor, and both names are in common usage.
Pryor is located in northeast Oklahoma at the intersection of US Route 69 and Oklahoma State Highway 20. The stream known as Pryor Creek flows past the west and south sides of the city.
According to the United States Census Bureau, the city has a total area of 6.5 square miles (16.9 km²), of which, 6.5 square miles (16.8 km²) of it is land and 0.04 square miles (0.1 km²) of it (0.31%) is water.